Basic Information
VIS ID
TVIS10004013
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
45381703/45342104 (Hg38)
End
45381703/45342104 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA7D
Nearest miRNA
hsa-mir-1183/Upstream/460304; hsa-mir-10399/Downstream/11613681;
Nearest TSS
ENST00000635602/Upstream/184275; ENST00000443714/Downstream/118608;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/183896, chr7-CpG: 137/Downstream/231683
Nearby gene
RAMP3(-157853) ; ADCY1(+232036) ;
Upstream sequence
TCATATGCTTAATATGCTATTCTGAAACCTCTTATTGCAATGTTTTTAATATAAATTCTTTTCAGAAACAATACCTTCTGGAGTTGCGTTTTCAACTTTA
Downstream sequence
agaatagagaacAGCAATACAgacttgcaatggggttacttcctgataaacccatcataagttgaaaatattgtaagttgaaaatgtattgaatacacct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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