Basic Information
VIS ID
TVIS10004044
Fusion event
HBV-MIR381HG integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q32.31
Reference genome
GRCh37/hg19
Start
101513069/101046732 (Hg38)
End
101513069/101046732 (Hg38)
Location type
ncRNA_intronic
Target gene
MIR381HG
Nearest miRNA
hsa-mir-1185-1/Upstream/194; hsa-mir-12121/Downstream/589;
Nearest TSS
ENST00000550708/Upstream/1575; ENST00000452349/Downstream/17419;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/163209, chr14-CpG: 48/Downstream/18574
Upstream sequence
gcccattgtctcacatgtcaaaggggaatcacattggcgtccatttcttggggctgctggggctgaacgagttaagacttgtacacggctcagagcagag
Downstream sequence
ccccgtggtcggcacttcgtaggtggtagCCAGGACCCTTGTGTGCTGTGAAACTATCATtggtggtggtggtggtggtggtggtggtggtTTTATGACT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate