Basic Information
VIS ID
TVIS10004053
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
191860071/191890941 (Hg38)
End
191860071/191890941 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/11452551; hsa-mir-1182/Downstream/825387;
Nearest TSS
ENST00000473358/Upstream/712; ENST00000491030/Downstream/267516;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/5209992, chr1-CpG: 56/Downstream/917561
Nearby gene
PRPF31(-1089283) ; RGS18(+267521) ;
Upstream sequence
TTTTACCCATATAAGAAAGCATGCTCTTTTTTTTTTTTTGCCTCAGGCTGCTAGGGTGGAGCTGAGTGAATTCAACATGTATTTGAATTGGAACTTGATT
Downstream sequence
TTGCTGTAACTTGTCAGCTTTAATATATTAATGATTTCAAATAATTTGAAGATGGGATCAGAATTTTTTCTTACGGTATCTGGAATTTTAGCATTAGTAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate