Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004057
Fusion event
HBV-SLIT3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
End
168180386/168753381 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-218-2-3p ; hsa-mir-218-5p ; hsa-mir-1343-3p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-214-3p ; hsa-mir-24-3p ; hsa-mir-3074-5p ; hsa-mir-3619-5p ; hsa-mir-3690 ; hsa-mir-4254 ; hsa-mir-4291 ; hsa-mir-4511 ; hsa-mir-6077 ; hsa-mir-646 ; hsa-mir-6783-3p ; hsa-mir-7152-5p ; hsa-mir-7-5p ; hsa-mir-761 ; hsa-mir-922
Nearest miRNA
hsa-mir-10397/Upstream/192408; hsa-mir-10523/Downstream/14765;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/173468, chr5-CpG: 94/Downstream/547044
Upstream sequence
tgggattacagatgcgtaccaccatgcctggctaatttttgtattttcttagagacaaaattttaccatgttggctaggctggtctcaaactcctgacct
Downstream sequence
CACATATTTCTGGGAAGAGAAGAGAGAATCAAGACGTGGTTGTAGACATCAGCTtgtatgtatgtgtgtgcttgtgtgtctgtgcctgtttgtatatatg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.