Basic Information
VIS ID
TVIS10004074
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
55361890/54495723 (Hg38)
End
55361890/54495723 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/1782976; hsa-mir-1243/Downstream/6426896;
Nearest TSS
ENST00000502981/Upstream/49000; ENST00000514582/Downstream/111408;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/261559, chr4-CpG: 182/Downstream/161519
Nearby gene
PDGFRA(-197478) ; KIT(+162205) ;
Nearest cancer related gene
PDGFRA(OG, -197478) ; KIT(OG, +162205) ;
Upstream sequence
caaaactccatctcaaaaaaaaaaaaaaaaaaaaaaaaaaaTTAGCATGTGATTCAGTCTACAGAGAACTAGATTAGTGAAGGAGGCATTGCAGCAGGAG
Downstream sequence
aaaaaaaaaaaaaaaaaagaagaagaaGAAGAAGAAGAATCCCCTCTCCGGAACCAGTCCTTTTGAAGGCCAGGGCAGTATCCAAGTGCTGTGGGGCTCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate