ME3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004088
Fusion event
HBV-ME3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
86331908/86620866 (Hg38)
End
86331908/86620866 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA11F
Target gene
ME3
miRNAs that regulate target gene
hsa-mir-30a-5p
Nearest miRNA
hsa-mir-10392/Upstream/342468; hsa-let-7a-2/Downstream/1555636;
Nearest TSS
ENST00000527297/Upstream/122742; ENST00000526206/Downstream/50956;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/189312, chr11-CpG: 82/Downstream/50787
Upstream sequence
gtgtgccttaatatcatacatctttttttgatcaaatattttaaaattcagacattttgctaattcaGCCAATCTCTCTGTCCTCTAGGGCCTCAGTCCA
Downstream sequence
GTTTCCTGAGGTTTTTAAAAAATCAGATCCATCTGACCTAGGCCCACTTGTCTTGGTGCATTTTCCCAGCAGAGCATGAGGTTTCTCATGCTTGTGGTTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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