Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004108
Fusion event
HBV-DIP2C integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
p15.3
Reference genome
Start
End
470684/424744 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-545-3p ; hsa-mir-505-3p ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-3529-3p ; hsa-mir-34a-3p ; hsa-mir-1281 ; hsa-mir-6881-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-4677-3p ; hsa-mir-1236-3p ; hsa-mir-877-3p ; hsa-mir-660-3p ; hsa-mir-5193
Nearest miRNA
hsa-mir-107/Downstream/216945;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/4288, chr10-CpG: 23/Downstream/47508
Upstream sequence
tgagccaccgctcctggccCACTCTGCCTTTTAAGAAAACTTACACAATTTCTATAAAAGTAAAATTGACACAGCCTTGAGACTTTTGAGAAAGGTACAC
Downstream sequence
ACCCAGGTGTCCAGAAGGAGCACAACCATCTCCCCAGAATGTCTTCTCACAACTCTTTACAATCTTTCATTCCCCACTCCCACCTACCTCTTCCAAGAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.