Basic Information
VIS ID
TVIS10004114
Fusion event
HBV-LOC105377731 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
172713256/173286253 (Hg38)
End
172713256/173286253 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
LOC105377731
Nearest miRNA
hsa-mir-10397/Upstream/371095; hsa-mir-12118/Downstream/17477;
Nearest TSS
ENST00000502646/Upstream/50896; ENST00000523205/Downstream/38033;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2194, chr5-CpG: 19/Downstream/7691
Nearby gene
NKX2-5(-50941) ; STC2(+28470) ;
Upstream sequence
ATCACTGCAGATGTTAGGAGCTGCATGTCAATGCAGGGGTCCCCAGACTCCTGGGGGACTCAGGCGAAGGGCTCTAAGGGTTGTTCCGAACATGGTGCCT
Downstream sequence
AGCCTATCAGCCATGGCATTAGCCcaaaacaaaaccaaaccaaacaaaacaaaaACTCACTAATGGTGGGCCCTGTCAAGACAAACTATTCCCTGAGGAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate