Basic Information
VIS ID
TVIS10004117
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
94849525/94383969 (Hg38)
End
94849525/94383969 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/537058; hsa-mir-11399/Downstream/159733;
Nearest TSS
ENST00000473358/Upstream/59400; ENST00000468860/Downstream/34486;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/136008, chr1-CpG: 101/Downstream/34000
Nearby gene
ARHGAP29(-146218) ; ABCD3(+34408) ;
Nearest cancer related gene
ARHGAP29(TSG, -146218) ;
Upstream sequence
aaaacgatgtgaatgtatttaattatgctgaactgtacacttaaacaatgataagttatctagtattttttactacatcaaaaaaTAGAGTTAAAAAaaa
Downstream sequence
gtgctccgaagaatgtctgatacatagtaagttctcTGTATGAGTTATCTGTGGTATCTCTTGCTTACTGATGTTGCTCTTTAACACTTGCATTTTCACT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate