VISDB Viral Integration Site DataBase

VIS ID

TVIS10004122

Fusion event

HBV-RHOB integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr2

Cytoband

p24.1

Reference genome

Start

End

20646734/20446973 (Hg38)

Location type

Promoter

Target gene

miRNAs that regulate target gene

hsa-mir-223-3p ; hsa-let-7b-5p ; hsa-mir-21-5p ; hsa-mir-335-5p ; hsa-mir-30a-5p ; hsa-mir-421 ; hsa-let-7c-5p ; hsa-mir-218-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-2053 ; hsa-mir-642a-5p ; hsa-mir-6801-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-627-3p ; hsa-mir-6845-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-6513-3p ; hsa-mir-2115-3p ; hsa-mir-6882-5p ; hsa-mir-595 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-7849-3p ; hsa-mir-494-3p ; hsa-mir-6507-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-186-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-3614-3p ; hsa-mir-590-3p ; hsa-mir-6083 ; hsa-mir-3163 ; hsa-mir-4282 ; hsa-mir-6749-3p ; hsa-mir-4469 ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-5196-3p ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3196 ; hsa-mir-3675-5p ; hsa-mir-4649-5p ; hsa-mir-6729-5p ; hsa-mir-6816-5p ; hsa-mir-1908-5p ; hsa-mir-342-5p ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-4787-5p ; hsa-mir-489-5p ; hsa-mir-5089-3p ; hsa-mir-6087 ; hsa-mir-608 ; hsa-mir-663a ; hsa-mir-6737-5p ; hsa-mir-6742-5p ; hsa-mir-6747-5p ; hsa-mir-6752-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6787-5p ; hsa-mir-6812-5p ; hsa-mir-6819-5p ; hsa-mir-6842-5p ; hsa-mir-7110-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-3125/Upstream/1098468; hsa-mir-10b/Downstream/4881667;

Nearest TSS

Nearest CpG islands

chr2-CpG: 157/Target, None/Upstream, None/Downstream

Nearest cancer related gene

RHOB(TSG, No orient, 0)

Upstream sequence

CTCCCCGGTCGCTGCCTCTCCCAGCCCGGCGGCCTGGGCCGTCAATCAAGCTGGCCCTGCCCCGCCCTCGGGCTGCAGGGGGCGGCCAATCAGAGCTAAG

Downstream sequence

CTCCGCAGCGATGAGCTCAGCCGGCTGGTTTCCCATTGGACGGCTATATTAAGAAAGTGGCCGGACTCTTTAAATAGCGGGCGCTAGGGCCGCAGCCCTC