Basic Information
VIS ID
TVIS10004127
Fusion event
HBV-TRA integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
22708349/22240466 (Hg38)
End
22708349/22240466 (Hg38)
Location type
Intronic
Target gene
TRA
Nearest miRNA
hsa-mir-6717/Upstream/1217080; hsa-mir-1185-1/Downstream/716484;
Nearest TSS
ENST00000550708/Upstream/13720; ENST00000553906/Downstream/25283;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/728909, chr14-CpG: 40/Downstream/348549
Nearby gene
OR4E2(-574111) ; DAD1(+325458) ;
Upstream sequence
ccttgtccatgccccttatgtcaagggaatcactggaaggcccactgccccaggagatgaaggtcctctgagtcagaagccactaaccagataatccagc
Downstream sequence
agcaggactgaggatgcccagggcaagcgccagcccatgccatcaccctcacagagccttgggtatgcttgaccattgagggccaggaggttcactgtct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate