Basic Information
VIS ID
TVIS10004143
Fusion event
HBV-LOC105370770 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
36780071/36487870 (Hg38)
End
36780071/36487870 (Hg38)
Location type
Intronic
Target gene
LOC105370770
Nearest miRNA
hsa-mir-1233-1/Upstream/560947; hsa-mir-10393/Downstream/484951;
Nearest TSS
ENST00000557528/Upstream/16854; ENST00000567573/Downstream/91741;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/941556, chr15-CpG: 35/Downstream/91388
Nearby gene
MIR4510(-560947) ; C15orf41(+91741) ;
Upstream sequence
cctgaatacaggagtaagagcaggactgACAGGAGGGACCAGGGAGAAAAGAAAAAAGGAGAGTGGAGTTACGGAGGAGAGGCAGGAAGGAAAGAAAAGG
Downstream sequence
GAGACTGTAGTTTCAGTTAAAAAATAATTTACAAaatatatacaacaatcaaaatgaatgaatttaccgtgtggatattcataatgcagcaatatagaaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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