Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004156
Fusion event
HBV-ALDH5A1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
Start
End
24535027/24534799 (Hg38)
Location type
UTR3
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-24-3p ; hsa-mir-30c-5p ; hsa-mir-210-3p ; hsa-mir-147b ; hsa-mir-4279 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-122-3p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6747-3p ; hsa-mir-561-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-4437 ; hsa-mir-6847-3p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-1283 ; hsa-mir-877-3p ; hsa-mir-5088-5p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-4252 ; hsa-mir-4520-5p ; hsa-mir-1273g-3p ; hsa-mir-29a-3p
Nearest miRNA
hsa-mir-3691/Upstream/5962919; hsa-mir-10398/Downstream/2612827;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/39357, chr6-CpG: 62/Downstream/110904
Upstream sequence
ATAAATATCTGATTATTTCCTGGCAGGCAACTACAGTAAAATCTCACACCTCAATTTTTCCAGATCTTGGAAGTACATTCATCAATGTCTACTGCAGTTT
Downstream sequence
TCCTGGTGTGGTGCTGCTCCCTCACCTCCAAAAGAGCAAAAGTACTTTCACCACAGTCAACCCAAAAGGGAAAGAATTTCTGTAATTGCCAACCCACTTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.