Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004173
Fusion event
HBV-MTOR integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
Start
End
11200377/11140320 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-99a-5p ; hsa-mir-520c-3p ; hsa-mir-373-3p ; hsa-mir-99b-5p ; hsa-mir-144-3p ; hsa-mir-100-5p ; hsa-mir-199a-3p ; hsa-mir-16-5p ; hsa-mir-744-5p ; hsa-mir-181b-5p ; hsa-mir-101-3p ; hsa-let-7c-5p ; hsa-mir-218-5p ; hsa-mir-496 ; hsa-mir-196b-5p ; hsa-mir-224-5p ; hsa-mir-128-3p ; hsa-mir-193a-5p ; hsa-mir-125a-5p ; hsa-mir-497-5p ; hsa-mir-3188
Nearest miRNA
hsa-mir-12136/Upstream/1172862; hsa-mir-101-1/Downstream/888838;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/40241, chr1-CpG: 60/Downstream/121881
Nearest cancer related gene
MTOR(OG, No orient, 0)
Upstream sequence
GTACTGTGAGTGAAATACCCTTAGGcagcagtccccaacctttttggcaccagggactagttttgtggaagacaattattccacagattgggtggggggc
Downstream sequence
ggggggatggttttcagatgatcatcaggcattagattctcataaggagcatgcaacctggatcccttgcatgcgcagttcataatacggttcatgctcc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.