Basic Information
VIS ID
TVIS10004183
Fusion event
HBV-MDFIC2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
GRCh37/hg19
Start
70272683/70223532 (Hg38)
End
70272683/70223532 (Hg38)
Location type
Intronic
Target gene
MDFIC2
Nearest miRNA
hsa-let-7g/Upstream/1174497; hsa-mir-12124/Downstream/1318438;
Nearest TSS
ENST00000440867/Upstream/223686; ENST00000641222/Downstream/60079;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/483475, chr3-CpG: 50/Downstream/841651
Nearby gene
SAMMSON(-208232) ; FOXP1(+731182) ;
Upstream sequence
ttgcttgaacccaggaggtggaggttgcagtgaaccgagattgcaccattgcactccagcctgggcaacaagagaaaaactccatctcaaaaaaaaaaaa
Downstream sequence
TTTGGAAAGGCTGAGGTTGTCTCCCCCACCAAAAATGAGAACTTGATTGAAAAATTATTGTCCTTCGGGCAGGTACAATGAGTCTTACAGGCTATTTCCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate