CDH11 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004193
Fusion event
HBV-CDH11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
65096276/65062373 (Hg38)
End
65096276/65062373 (Hg38)
Location type
Intronic
Target gene
CDH11
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-200c-3p ; hsa-mir-27b-3p
Nearest miRNA
hsa-mir-1225/Upstream/7290021; hsa-mir-11401/Downstream/2139948;
Nearest TSS
ENST00000527434/Upstream/2695; ENST00000562656/Downstream/9840;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/111368, chr16-CpG: 230/Downstream/58380
Nearest cancer related gene
CDH11(TSG, No orient, 0)
Upstream sequence
GGGCAACTTCCAGACAACCAAGAAATCCGCTTATTTGCAAGTTTCTGGAGTATGCAAATCTCCATATTCACAAAGTCAGAGAAGTACTGCAAacacacac
Downstream sequence
acacacagagacacacacacTGCAGTGTTTGTTGTATGCCAAAATAGTCACAGCCTCCCGCTATCTTTCCATAGTAAGAAAAGTAAACTGCATAGTCCAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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