Basic Information
VIS ID
TVIS10004216
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
30018263/30018156 (Hg38)
End
30018263/30018156 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/12862164; hsa-mir-103a-1/Downstream/1917946;
Nearest TSS
ENST00000502646/Upstream/622175; ENST00000506396/Downstream/1175594;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1089626, chr5-CpG: 37/Downstream/1175689
Nearby gene
LINC02064(-622180) ; CDH6(+1175499) ;
Upstream sequence
ATGGAGCATTCTCTCATTACTATCTTCAGTTCTTCTACTTGAGATAGTTCTGTGCCTCTTAAAATCAAGACAAATTCAACCAAAAGAAGGACTTTAGGAG
Downstream sequence
gaaagtctttcccaatgaaaactaatatctaaggactggaagaggtgaccacttccaatgttcagacactaatccaaggctacgaggatcaccaaagatc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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