Basic Information
VIS ID
TVIS10004219
Fusion event
HBV-chr16 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
64972773/64938870 (Hg38)
End
64972773/64938870 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/7166518; hsa-mir-11401/Downstream/2263451;
Nearest TSS
ENST00000527434/Upstream/574089; ENST00000562656/Downstream/34079;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/2902140, chr16-CpG: 19/Downstream/11908
Nearby gene
CDH11(+7910) ;
Nearest cancer related gene
CDH11(TSG, +7910) ;
Upstream sequence
AGAACGTAATAATACTATAGCCTCTGTGATCTTCATTTGGTTCACAATATCATCCCTATTAATGAATAGGACTGAAAGAAAAAACTAAATGAAAATTCTC
Downstream sequence
ACTCAAATCCATAAATTAAAAAGTCTAATGTTGATAACACTCATTGCTattcacttgttcgatcaaaaattgtttattggaccctaaaattctgcaggca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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