VISDB Viral Integration Site DataBase

VIS ID

TVIS10004232

Fusion event

HBV-chr5 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr5

Cytoband

q11.2

Reference genome

Start

End

56196564/56900737 (Hg38)

Location type

Promoter;downstream

Fragile sites / regions

Target gene

MAP3K1 ; SETD9

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-423-3p ; hsa-mir-125a-5p ; hsa-let-7g-5p ; hsa-mir-34a-5p ; hsa-let-7a-5p ; hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-153-5p ; hsa-mir-3646 ; hsa-mir-6864-5p ; hsa-mir-6126 ; hsa-mir-1252-5p ; hsa-mir-4635 ; hsa-mir-93-3p ; hsa-mir-4680-3p ; hsa-mir-1207-3p ; hsa-mir-4699-3p ; hsa-mir-4762-3p ; hsa-mir-4539 ; hsa-mir-1252-3p ; hsa-mir-5585-3p ; hsa-mir-4703-3p ; hsa-mir-509-3p ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-323a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-451a ; hsa-mir-1273e ; hsa-mir-1827 ; hsa-mir-302f ; hsa-mir-3664-3p ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4649-3p ; hsa-mir-4695-5p ; hsa-mir-485-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-665 ; hsa-mir-6808-5p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-873-5p ; hsa-mir-940

Nearest miRNA

hsa-mir-10397/Upstream/1391811; hsa-mir-103a-1/Downstream/1629306;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/83655, chr5-CpG: 113/Downstream/8398

Upstream sequence

tttttgttttttgggttttttttttgttgttgttgttctttttgAAGCTTATGGTATTGCTTGGAACCTTAAAACATAAAAGAGCAGGGGGACGAATCTG

Downstream sequence

AAACTAGAAACGCACAGGGTCAGGGAAATCAAGAGAGGAGAATGTTTTAAAGAAAGGTCAGTAATTTCAAAAGCCACAGACGTCAGGTAAGATAAGAACT