Basic Information
VIS ID
TVIS10004246
Fusion event
HBV-chr9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q22.32
Reference genome
GRCh37/hg19
Start
98145620/95383338 (Hg38)
End
98145620/95383338 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-1/Upstream/297244; hsa-mir-12126/Downstream/1980216;
Nearest TSS
ENST00000422679/Upstream/65629; ENST00000605700/Downstream/24324;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/31958, chr9-CpG: 401/Downstream/122588
Nearby gene
FANCC(-65629) ; PTCH1(+59644) ;
Nearest cancer related gene
PTCH1(OG, +59644) ;
Upstream sequence
AGAATGATTTTCTTGGTTTTACTTCTAACTGTGGTAGGTGCTGGCAGAGGCTGCCTGTCCGCTGGGGTAGTGAGGAGACTATGCAGCGTGTTTTTGCTCC
Downstream sequence
AAATGACTTGCAGATTTTACACCTAACAATGAAAAAATTTATTTACATAAAATAGGATCTGCTGAGGGGACTCTCGTGAATTAGTTTCGGGGTAGCTTGT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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