Basic Information
VIS ID
TVIS10004256
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
97303026/97673714 (Hg38)
End
97303026/97673714 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/1453958; hsa-mir-10399/Downstream/289944;
Nearest TSS
ENST00000635602/Upstream/531033; ENST00000495916/Downstream/58194;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/555836, chr7-CpG: 137/Downstream/58106
Nearby gene
SDHAF3(-491951) ; TAC1(+58245) ;
Nearest cancer related gene
TAC1(OG, +58245) ;
Upstream sequence
AACTGCCATTAGAAATAGAAGGAAACCCATTTTATCTGGGTTACTTTGACAGATGTAACTCTCACAAAGGATGAATATCAACCACCAGCACCCTCTTGTC
Downstream sequence
ctgggcatggtggcatgcacctgtagtcctagctattcaggaggctaaggcaggaaagacacttgagcccaagagttctagatggcagtgagctatgatt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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