Basic Information
VIS ID
TVIS10004261
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q42.11
Reference genome
GRCh37/hg19
Start
224112267/223924565 (Hg38)
End
224112267/223924565 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/3723946; hsa-mir-1182/Downstream/332475;
Nearest TSS
ENST00000473358/Upstream/78593; ENST00000618397/Downstream/69697;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/78004, chr1-CpG: 63/Downstream/67995
Nearby gene
TP53BP2(-78593) ; FBXO28(+189522) ;
Nearest cancer related gene
TP53BP2(TSG, -78593) ;
Upstream sequence
gatcacttgagtccatgaggtcaaggctgcagtgagtcatgtttgcaccactgcactctagcctaggtgacagagctagttcctatcaaaaaaaaaaaaa
Downstream sequence
aaaaaaaaaaaaaGAATGGAGAGAATgctacatgagagaaaggatcttatttatcatgttcacctcccaagaggtgaacatatcccccaaagcctgatag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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