Basic Information
VIS ID
TVIS10004285
Fusion event
HBV-LOC105369791 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
59501119/59107338 (Hg38)
End
59501119/59107338 (Hg38)
Location type
Intronic
Target gene
LOC105369791
Nearest miRNA
hsa-mir-1228/Upstream/1282646; hsa-let-7i/Downstream/3153021;
Nearest TSS
ENST00000382841/Upstream/186699; ENST00000549465/Downstream/303833;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/186667, chr12-CpG: 76/Downstream/488532
Nearby gene
LRIG3(-186800) ; SLC16A7(+488702) ;
Upstream sequence
cacaaaagtcttatctctcctatctaactagagctttgaccaacagttctcAAAAATATGTTAGAAGGAAGGTTTCTCTGGAGTCAATGTGAGATATATA
Downstream sequence
GGTGAAAAAATATCAGGAGACCTTTTCAATAGTTCTGGGAAGATGATGCAGGTTTGAATTGAAAAGCAGTGGCAGCAAAGATAGAAAAAATACACTTTTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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