IQGAP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004290
Fusion event
HBV-IQGAP2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
75843209/76547384 (Hg38)
End
75843209/76547384 (Hg38)
Location type
Intronic
Target gene
IQGAP2
miRNAs that regulate target gene
hsa-mir-499a-5p ; hsa-mir-208b-3p ; hsa-mir-208a-3p ; hsa-mir-549a ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-548e-5p ; hsa-mir-92a-1-5p
Nearest miRNA
hsa-mir-10397/Upstream/3668721; hsa-mir-103a-1/Downstream/6292771;
Nearest TSS
ENST00000502646/Upstream/142960; ENST00000504815/Downstream/25;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/143049, chr5-CpG: 111/Downstream/167911
Nearest cancer related gene
IQGAP2(TSG, No orient, 0)
Upstream sequence
gaccagcatggaggtataaaggcctggtcttctgggcccagtcaggagagctctggagctcctcccatgtttaaaactcccctagtaatggctgggcctt
Downstream sequence
ATATTGAATACTTGCTTGGGGCTTAGAAGAGGGAAGTCAAGTGTAGGAAGGAGTTGTGGCAATTTAAGTAAGTTTACAATGATCTTATTAAGCTTGTTGC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate