Basic Information
VIS ID
TVIS10004305
Fusion event
HBV-chr13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
51165163/50591027 (Hg38)
End
51165163/50591027 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-15a/Upstream/541826; hsa-mir-1267/Downstream/757540;
Nearest TSS
ENST00000623511/Upstream/63578; ENST00000413510/Downstream/124456;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/457144, chr13-CpG: 62/Downstream/252208
Nearby gene
DLEU1(-62384) ; DLEU7(+121596) ;
Nearest cancer related gene
DLEU1(TSG, -62384) ;
Upstream sequence
GCACAGAGCTCTTGCTCTGTGGGCTTCCCTGGAGCCATAGCCTGAGCCATGCCAGCGAAGTCAGAGAAGAGCAGAAGCTCAAACATCCCAAGAATTGTGT
Downstream sequence
TCCATAAAAGGCTCACTTTCTAGTCACACCTTGTACACATTCTCTAGAGAGAATCACCTATTTCTTATTTTTGAAATGTTCTTTAATGTcatagaattca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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