Basic Information
VIS ID
TVIS10004343
Fusion event
HBV-chr17 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
45795299/47717933 (Hg38)
End
45795299/47717933 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/744833; hsa-mir-10226/Downstream/314949;
Nearest TSS
ENST00000595228/Upstream/22248; ENST00000581328/Downstream/15311;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/8377, chr17-CpG: 104/Downstream/15290
Nearby gene
TBKBP1(-5870) ; TBX21(+15311) ;
Upstream sequence
GGGCACAGGTGGGTCTCCTTCCCACGGATGGTCAAGCAGTTGCATTGTCACCACACCACCCTCCAGACTCACCCTGTCACATCACCCCAGATACACAAAG
Downstream sequence
CACACGGACCGACCCAGTTCCATGCTCATCCCTTCCCCACCTACCAGGCTTCCAGGGACACCCACGTGCAGGGACACACTCCTCCCAACACACACAGCCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate