ALK _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004349
Fusion event
HBV-ALK integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p23.2
Reference genome
GRCh37/hg19
Start
29499639/29276773 (Hg38)
End
29499639/29276773 (Hg38)
Location type
Intronic
Target gene
ALK
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-96-5p
Nearest miRNA
hsa-mir-1301/Upstream/1280324; hsa-mir-10b/Downstream/3255380;
Nearest TSS
ENST00000437798/Upstream/49120; ENST00000421411/Downstream/42438;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/160730, chr2-CpG: 147/Downstream/643192
Nearest cancer related gene
ALK(OG, No orient, 0)
Upstream sequence
ctataaaatggatggacctcaaagacgtgatgctaagttaaagaagccagacagtaggtgaaagaccgcctattgaatgattccattgatagaaaatgtc
Downstream sequence
tagaaaaggtaaatctgtggggccagaaagcagattagtggttgtctggggctgggagtgggcacaggattgaccgcagactagcacctaggcttttttt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate