Basic Information
VIS ID
TVIS10004351
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
4020350/4020236 (Hg38)
End
4020350/4020236 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/2311368; hsa-mir-10397/Downstream/2807617;
Nearest TSS
ENST00000502646/Upstream/6587; ENST00000503415/Downstream/21528;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/57838, chr5-CpG: 39/Downstream/845968
Nearby gene
IRX1(-418833) ; LINC02114(+753244) ;
Nearest cancer related gene
IRX1(TSG, -418833) ;
Upstream sequence
ACCTTCTATTTCCTGTGTTTTCACCCAAACTGATTTTGGTCTCTCAAAAATTCTGAAAACAAATAAGGAAGTTATATACATAAAGTATAcagtggtccct
Downstream sequence
CTGGGAGATCAAGGCCCAGCCCTTTCTGCCCAGCATCGAAGTGGGCAGGATGGAGAGGAGATTAGAAGGCTCACTCTTGGAGCTGCCCGGGAAAATGAAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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