Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004355
Fusion event
HBV-SNRPB integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
p13
Reference genome
Start
End
2444781/2464135 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-376b-3p ; hsa-mir-5704 ; hsa-mir-376a-3p ; hsa-mir-4457 ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-6888-5p ; hsa-mir-4759 ; hsa-mir-577 ; hsa-mir-4681 ; hsa-mir-6856-3p ; hsa-mir-4428
Nearest miRNA
hsa-mir-6869/Upstream/1071174; hsa-mir-1-1/Downstream/188642;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/60345, chr20-CpG: 47/Downstream/6294
Upstream sequence
TGTGTGCCAACACCATTCTTCCTCCATCCAAGACTATGAGTTATCCCTGAAGCAGGGTAGAACTTAAGAGTAAGTCTAGAGAAACATGCCACAACTCAAC
Downstream sequence
CACCTATATGCACTCCTGTGAAAGTTAAACCAAGAGCAAAGGGCCAGGGTTCCACTCAGGGTTCAGCAGGCAAGGCATTAaagggacatgagatccattc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.