Basic Information
VIS ID
TVIS10004358
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
57806943/56894384 (Hg38)
End
57806943/56894384 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/13998109; hsa-mir-10400/Downstream/4820404;
Nearest TSS
ENST00000518652/Upstream/237919; ENST00000519314/Downstream/85728;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/446128, chr8-CpG: 77/Downstream/98757
Nearby gene
LINC00968(-334561) ; IMPAD1(+63545) ;
Upstream sequence
CCCCTGGCAAGGATTATGGGTTAACTGGAAAATTTCAGGCTGATGCTTCAAGTTTTGCAGTGAGCGCCTAGCTCATGGGAACACTAAAATCGAGTAATAC
Downstream sequence
agccactatagtacaaggaataagtacaatgataaggaaatttgttcaaatcggagcatggaTGCCAAGATAGAAGTTGTCTCATAAGCCTAGGTGAACA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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