TSC2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004362
Fusion event
HBV-TSC2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2105468/2055467 (Hg38)
End
2105468/2055467 (Hg38)
Location type
Exonic
Target gene
TSC2
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-296-3p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-3176/Upstream/320401; hsa-mir-11401/Downstream/34728;
Nearest TSS
ENST00000527434/Upstream/1548; ENST00000467949/Downstream/678;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/78, chr16-CpG: 25/Downstream/7400
Nearest cancer related gene
TSC2(TSG, No orient, 0)
Upstream sequence
GCGTCCTCGCAAACTGCCGCCGCTTCTCCCCCAGCTGACTTTGTCCTGCAGTGGATGGATGTTGGCTTGTCCTCGGAATTCCTTCTGGTGCTGGTGAACT
Downstream sequence
TGGTCAAATTCAATAGCTGTTACCTCGACGAGTACATCGCAAGGATGGTTCAGTAAGAAAAGAATTGAGATCCTGTTCTGATAATGGTCCTAAGTTCAGC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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