ZC3H15 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004367
Fusion event
HBV-ZC3H15 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
187345633/186480906 (Hg38)
End
187345633/186480906 (Hg38)
Location type
Promoter
Target gene
ZC3H15
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-96-5p ; hsa-mir-122-5p ; hsa-mir-143-5p ; hsa-mir-24-3p ; hsa-mir-3135b ; hsa-mir-3622b-5p ; hsa-mir-3652 ; hsa-mir-4284 ; hsa-mir-4430 ; hsa-mir-504-3p ; hsa-mir-5693 ; hsa-mir-5698 ; hsa-mir-6499-3p ; hsa-mir-8057
Nearest miRNA
hsa-mir-10b/Upstream/2101862; hsa-mir-1244-1/Downstream/1816586;
Nearest TSS
ENST00000437798/Upstream/124133; ENST00000477672/Downstream/5250;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/741723, chr2-CpG: 87/Downstream/4864
Upstream sequence
atgtggaatgagtaagtagccgtatttaagccaactcaaGGCAAAATTACCAGGCCCTGTTGATACTCTACTACCCAAAAAGTTCTTCTCCCTAGGGTCC
Downstream sequence
CTGCCACAGTTGCCTCTTTTCACTTTCCTCCCTAAACTTCTTTTTCTGTATTTACCTTTTAAACATTGTTCCTCACATTTTTATTCTTTTTTGGCTCTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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