Basic Information
VIS ID
TVIS10004376
Fusion event
HBV-PGR-AS1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
101023406/101152675 (Hg38)
End
101023406/101152675 (Hg38)
Location type
ncRNA_intronic
Target gene
PGR-AS1
Nearest miRNA
hsa-mir-10392/Upstream/4811149; hsa-let-7a-2/Downstream/367145;
Nearest TSS
ENST00000527297/Upstream/22151; ENST00000532529/Downstream/302902;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/22969, chr11-CpG: 114/Downstream/429951
Upstream sequence
ctgtgtccatgagttttcattgttcaactcccactcaggagtgagaacatgaagtagaacaccaggatttatttctcttatctaattgtaactttgtacc
Downstream sequence
cattgagtatcctcttcccatcctcccctttcccctcctctctccagtttctggtgaacattctactatctgcttctgtgatatcaatgaatttttaaaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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