LANCL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004377
Fusion event
HBV-LANCL1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q34
Reference genome
GRCh37/hg19
Start
211319990/210455266 (Hg38)
End
211319990/210455266 (Hg38)
Location type
Exonic
Target gene
LANCL1
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-4666a-5p ; hsa-mir-218-5p ; hsa-mir-1287-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-3168 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10b/Upstream/2700385; hsa-mir-1244-1/Downstream/1970997;
Nearest TSS
ENST00000437798/Upstream/14521; ENST00000416344/Downstream/5209;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/229814, chr2-CpG: 34/Downstream/21191
Upstream sequence
ACTGCCAGGGGGCCTGCATCCCCACAAAGGAAGGTGATGGAGCGCTTGGTTAAGCAGTTCAGACTTTGCTTTACATAGCCATGTGCTAACTGTAGGTAGG
Downstream sequence
CAGGGTCCCCAAATACATCATAAAGATGTAAGTAAAGCACAGCAATACCTGAAAAAAAAAAAAGGAAACAATGTAAAGATGAGGAAAGGCAGTTATTTTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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