TPH2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004401
Fusion event
HBV-TPH2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
72380479/71986699 (Hg38)
End
72380479/71986699 (Hg38)
Location type
Intronic
Target gene
TPH2
Nearest miRNA
hsa-let-7i/Upstream/2401876; hsa-mir-1178/Downstream/7432558;
Nearest TSS
ENST00000382841/Upstream/47722; ENST00000550403/Downstream/44573;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/146844, chr12-CpG: 160/Downstream/285204
Upstream sequence
GGATAAAGCTTCAATACTTCAGCCACCCTTCTTTTTTTTTTTTTTTTTTAGCAGATTCAAAGCAGGATTCCTTATGTCACTCTCCCCTACCCCTGCACCC
Downstream sequence
AGTTCTGTTTTCCTTGTGCGGAGCCCATAATCCAAAATTAGCACTTAGAAGCACCTGGCCCAAATCAAAATTTATATTCCTTCAGCACTCTGTAGTCAGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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