Basic Information
VIS ID
TVIS10004415
Fusion event
HBV-LOC105375451 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
110231685/110591629 (Hg38)
End
110231685/110591629 (Hg38)
Location type
Intronic
Target gene
LOC105375451
Nearest miRNA
hsa-mir-10525/Upstream/8120098; hsa-mir-10399/Downstream/4061716;
Nearest TSS
ENST00000635602/Upstream/56875; ENST00000464835/Downstream/371936;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2021167, chr7-CpG: 68/Downstream/970394
Nearby gene
EIF3IP1(-631415) ; IMMP2L(+71421) ;
Upstream sequence
AGGCTGGTATTTTAGATGCCTACTTAGTTATTCCTAGGTTTGCCTATCATTAGGTAAGGTTTATATCAATTTTAAAAAATCAACCAAAGCACAATAGCTA
Downstream sequence
CAGCCTTCCACAGAGCCAAACATAGACATGTCTGTAATCTCTGGACACTAAGAAATAAGCTTCTTACAGACAGAATCTGGAAAGATGTCTGCCAAGAGTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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