Basic Information
VIS ID
TVIS10004418
Fusion event
HBV-chr22 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr22
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
16633733/15344228 (Hg38)
End
16633733/15344228 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-3/Downstream/2419952;
Nearest TSS
ENST00000624155/Upstream/39672; ENST00000252835/Downstream/183931;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/2528594, chr22-CpG: 65/Downstream/166575
Nearby gene
OR11H1(-183929) ; CCT8L2(+437915) ;
Upstream sequence
tgccactgcactccagactgggcaacagagagagactccatctccaaaggaaaaaaaaaaaaaaagaaaaaTACCCTTCATTGCTGGTGCTGGTGCACAT
Downstream sequence
GGAAAGGTATGGATACCCAAGATTCCTACTGGGGAAGAGGTGGGGTTCTTAGATATTCATGCAAAAGGGGAATATGTAATGTTGAAGCTCTGTCTGTGTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate