Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004421
Fusion event
HBV-LOXL2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
Start
End
23271495/23413982 (Hg38)
Location type
Promoter
Target gene
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-29b-3p ; hsa-mir-218-5p ; hsa-mir-410-5p ; hsa-mir-4465 ; hsa-mir-498 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-4679 ; hsa-mir-3691-3p ; hsa-mir-4677-3p ; hsa-mir-5697 ; hsa-mir-511-3p ; hsa-mir-595 ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-29b-2-5p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-376a-5p ; hsa-mir-6793-5p ; hsa-mir-194-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p
Nearest miRNA
hsa-mir-124-1/Upstream/1168945; hsa-mir-10400/Downstream/1539814;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/9628, chr8-CpG: 81/Downstream/43206
Upstream sequence
atcccagcagcactttgggaggccgaggcaggcggatcgcttaagctcaggagttccattccagcctgggcaacatggcgaagccacttgtctacaaata
Downstream sequence
tccacgcctgctcatggcctgatagctcatttttctttttcttttcttttttctttcttttttttttttttagacagagtctcaagagcagtggcacgat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.