Basic Information
VIS ID
TVIS10004427
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
92132450/91666893 (Hg38)
End
92132450/91666893 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/5309206; hsa-mir-11399/Downstream/2179939;
Nearest TSS
ENST00000473358/Upstream/153766; ENST00000461218/Downstream/45470;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/119794, chr1-CpG: 123/Downstream/218463
Nearby gene
CDC7(-141129) ; TGFBR3(+13450) ;
Nearest cancer related gene
TGFBR3(TSG, +13450) ;
Upstream sequence
taacagaatagatgaaaagagttaaatttttcttagctttagtttggtagggctttcccccgggactacggccatgactctggagggggtggtgctttct
Downstream sequence
tgactcgggtgtgatgagtccatccttttttttttttttttttttttttgctgtacaaacagcagtcttggtggttagcagcacaaggtagggtccttcc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate