Basic Information
VIS ID
TVIS10004429
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
76245875/75536159 (Hg38)
End
76245875/75536159 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA6D
Nearest miRNA
hsa-mir-10398/Upstream/107686; hsa-mir-10524/Downstream/3003104;
Nearest TSS
ENST00000381078/Upstream/42421; ENST00000493959/Downstream/65350;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/251041, chr6-CpG: 121/Downstream/65455
Nearby gene
FILIP1(-42379) ; SENP6(+65747) ;
Upstream sequence
cacttaaaatataatggcagaatgaataaaaaaatccaccaaccaaatatctgctgtcttcaagagacttatctaacacataaggacttatgtaaactta
Downstream sequence
aaaaaaaaaaaaaaaaaaaaaaaGTTGCATGGTTTCTACATTTTACATGAAGCAGCCACCaaaaataataataacataataataataaCATGAAGTGGTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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