Basic Information
VIS ID
TVIS10004433
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
112807176/112936453 (Hg38)
End
112807176/112936453 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10392/Upstream/1422938; hsa-let-7a-2/Downstream/513570;
Nearest TSS
ENST00000527297/Upstream/149149; ENST00000617166/Downstream/24794;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/645975, chr11-CpG: 178/Downstream/25349
Nearby gene
PRPF31(-380651) ; NCAM1(+24793) ;
Upstream sequence
aatcccagctactcgggaggctgaggcaggaggttcgattgaacccgggaggcagaggttgcagtgagccaagatcatgccatcgcactccagcctgggc
Downstream sequence
agcaacaagagcgaaactcagtctcaaaaaaaaaagaaaaaaaaatcagtagatcccatatgtgtagccctatttctgaatagacctctattctccataa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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