Basic Information
VIS ID
TVIS10004458
Fusion event
HBV-LOC107984183 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
123387324/121627810 (Hg38)
End
123387324/121627810 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
LOC107984183
Nearest miRNA
hsa-mir-107/Upstream/1669218; hsa-mir-202/Downstream/789155;
Nearest TSS
ENST00000439456/Upstream/11971; ENST00000447943/Downstream/108493;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/18591, chr10-CpG: 125/Downstream/299647
Nearby gene
FGFR2(-29352) ; ATE1(+112612) ;
Upstream sequence
tagaaaaccagttgttaaacatttgccagtacaccactgCCTATGTGATACCAAGCCCTCCTTCCCCTCACTCTGCCTGCTTGTACATGTCTTAATGCTC
Downstream sequence
TGGAGCCACCAGCCAGTCTCTCCAGTTTCGACCATGTTATCCATTTTCTCCCAAGACCCATCTGAGTGCCGCTCAACCCTTCTGCTTGTCCCTGCCAATT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate