Basic Information
VIS ID
TVIS10004459
Fusion event
HBV-LOC105377700 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
162721899/163294893 (Hg38)
End
162721899/163294893 (Hg38)
Location type
Intronic
Target gene
LOC105377700
Nearest miRNA
hsa-mir-10397/Upstream/2809443; hsa-mir-103a-1/Downstream/4870952;
Nearest TSS
ENST00000502646/Upstream/37906; ENST00000506186/Downstream/142400;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1746515, chr5-CpG: 26/Downstream/142485
Nearby gene
GABRG2(-1139354) ; CCNG1(+142678) ;
Upstream sequence
CCAGAGTCAACCTAAAATCCCTCCATTGCCAACCACTGCAGCCACATTGCAAGTCCTTGGGATCAGATAATAACACAATCTAGAATCCACCTTCTCTCCC
Downstream sequence
ACGATAGTCCCCCAAAACTGAAATAAAGCTTGTTTGTAAAAAAAAAAAAAAAATGGAAGTTCCAACAACTTTAAAATATGTTTCCATTGTTAATAACAAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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