Basic Information
VIS ID
TVIS10004460
Fusion event
HBV-KIAA0825 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q15
Reference genome
GRCh37/hg19
Start
93647033/94311328 (Hg38)
End
93647033/94311328 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5B
Target gene
KIAA0825
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10397/Upstream/690540; hsa-mir-103a-1/Downstream/1767810;
Nearest TSS
ENST00000502646/Upstream/199629; ENST00000508383/Downstream/165856;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/199597, chr5-CpG: 77/Downstream/306880
Upstream sequence
CTTTGGATCGTCTTAGCTGGCTCAATGGCTGCAGTGAACCACGAGGGCAGGTGCTGCATCTGATTCCTTCCCTACACACGCCCCAGCAGGGCACATGCCA
Downstream sequence
TGACTAATAAAAGTTAGAAAACTATATTTCTTATATATGGTCTTGTTCAAACCTACATTCATTAAAGCTTTGAAGAATAAGCTGAATTTATATTTTTAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate