Basic Information
VIS ID
TVIS10004470
Fusion event
HBV-LINC00358 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
62607730/62033597 (Hg38)
End
62607730/62033597 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA13B
Target gene
LINC00358
Nearest miRNA
hsa-mir-1297/Upstream/833717; hsa-mir-1267/Downstream/3932733;
Nearest TSS
ENST00000623511/Upstream/4049; ENST00000455977/Downstream/178980;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1635686, chr13-CpG: 36/Downstream/1777989
Upstream sequence
GGTAATGGAGAGATCAGAACAAAAGGCCTGGGGGGATTATGAGTCTAAAGACCACTTCATCAAAAATTTGAAGTGAGGAGAATCTATCAAGTAGGAAGGC
Downstream sequence
AACAGAACCATTTATTCAGCTCATAAAAGAGACTTTAGATGATTCTTGTTGAGATTTTCTAAGCAAAAAACTTGTAGTGAGGGCACAGCAAAAACTGTAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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