Basic Information
VIS ID
TVIS10004479
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
58344368/60677135 (Hg38)
End
58344368/60677135 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/2225977; hsa-mir-5011/Downstream/6404449;
Nearest TSS
ENST00000575820/Upstream/304360; ENST00000587582/Downstream/225591;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/707240, chr18-CpG: 98/Downstream/656315
Nearby gene
MC4R(-304367) ; CDH20(+813407) ;
Upstream sequence
agattaggagggggcttaggtggagcatcaacggcacctactgcaGTATATTTAACTGAAGAGCCCACACCAGCTTCTGATGCCTAGAAAAAGTTCCTCt
Downstream sequence
ttttttttttttttttttttgacagagtcttgctttgtcacacaggctagagtgcagtggagcaatctcagctcactgcaacctctacctcccaagttca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate