VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10004480

Fusion event

HBV-ZNF620 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Nontumor

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

27703150

Virus Sequence

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Host Sequence

Chromosome

chr3

Cytoband

p22.1

Reference genome

GRCh37/hg19

Start

40542771/40501280 (Hg38)

End

40542771/40501280 (Hg38)

Location type

Promoter

Target gene

ZNF620

miRNAs that regulate target gene

hsa-mir-510-3p ; hsa-mir-580-3p ; hsa-mir-1304-5p ; hsa-mir-1251-3p ; hsa-mir-494-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-370-5p ; hsa-mir-3912-5p ; hsa-mir-2054 ; hsa-mir-4662a-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4733-5p ; hsa-mir-4671-3p ; hsa-mir-143-5p ; hsa-mir-6080 ; hsa-mir-4328 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4496 ; hsa-mir-5683 ; hsa-mir-7844-5p ; hsa-mir-4289 ; hsa-mir-548an

Nearest miRNA

hsa-mir-12127/Upstream/1363014; hsa-let-7g/Downstream/3612932;

Nearest TSS

ENST00000440867/Upstream/23300; ENST00000433723/Downstream/4712;

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/23923, chr3-CpG: 25/Downstream/4620

Upstream sequence

GGTGATTCAAACTGCAATAGAATTTGCAGTGTCTTGGGATCATTATGATGGTGGTGTTTTGAATATTAGAAGTGTATCCAGATATAGGAGGTAGGGAATA

Downstream sequence

tagtgcaatggcacgagctcagctcgctgcaacctccacctcccaggttcaagcgattctcctacctcagcctcccaagtagctgggactataggtgccc

Reference

Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.