PPP2R2C _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004483
Fusion event
HBV-PPP2R2C integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
6421671/6419944 (Hg38)
End
6421671/6419944 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA4A
Target gene
PPP2R2C
miRNAs that regulate target gene
hsa-mir-142-3p
Nearest miRNA
hsa-mir-378d-1/Upstream/496616; hsa-mir-12113/Downstream/890506;
Nearest TSS
ENST00000502981/Upstream/35118; ENST00000504960/Downstream/1174;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/41126, chr4-CpG: 222/Downstream/50504
Nearest cancer related gene
PPP2R2C(TSG, No orient, 0)
Upstream sequence
TGTTTATCTCCTCAGCTAGAAATACacatacatacacacacatatatatgcatgcatatatgcatacaCGAGCTCGCAATGTTTGCAAATTGCAAatata
Downstream sequence
taactagtgacatacacaagaaccctatttccaaataaggtcacattctgaggtTCCAAGTGGACATTATTCTTGAGAGAAGGACACATTTAAACGCACG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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