Basic Information
VIS ID
TVIS10004495
Fusion event
HBV-chr14 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
83266724/82800380 (Hg38)
End
83266724/82800380 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/5534090; hsa-mir-1185-1/Downstream/11147846;
Nearest TSS
ENST00000550708/Upstream/4159; ENST00000554753/Downstream/217764;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1266290, chr14-CpG: 45/Downstream/2729770
Nearby gene
PRPF31(-1177319) ;
Upstream sequence
cacgcgcacacacacacacacacacacacacacaATCTGAGATAATCGGGTGGACAAAGAGCATAACGGGATTTGTCTAATAACTGCCTTGATGCCCTTC
Downstream sequence
AGAATGACCTTGGCTTTGCCCAAAAGCACTTGATTTGGCTACTGCCGTCACCTTTCGGCCTATATAAGTCAACCAAGGTTGATCAGTAACTGTGGCGAAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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