Basic Information
VIS ID
TVIS10004500
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
GRCh37/hg19
Start
226977006/226789305 (Hg38)
End
226977006/226789305 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/867163; hsa-mir-1182/Downstream/1152285;
Nearest TSS
ENST00000473358/Upstream/49982; ENST00000521431/Downstream/80879;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/50453, chr1-CpG: 83/Downstream/81039
Nearby gene
ITPKB(-50130) ; PSEN2(+81267) ;
Upstream sequence
ttacCATACCTGTAAAGCACTAACTGCTCTTGGAGTTACCGTGTCTTTGATGCAACAAGGGCTGAATCAGGACTTGATTAACTTCACCAACTTGCTGCCT
Downstream sequence
GCCTTAGCTTCTGGGTTCATGCTCAGCCAGCTTGAGTCGGGACACTCTGAAATTTATATGTATATATTCACTACATCCTACAAATATTGGAACAGCCATT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate